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In a similar way, glutamate is necessary for the brain to learn and function, however too much glutamate can make it hard to calm oneself and focus

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Int J Dev Neurosci 37:5257 Furukawa S, Yang L, Sameshima H, Ikenoue T (2014) Repetitive administration of acetylcholine receptor agonist rescues brain inflammation and brain damage after hypoxia-ischemia in newborn rat

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The combined use of probiotics and prebiotics has shown a synergistic effect in clinical settings, effectively regulating gut microbiota and improving symptoms and quality of life in IBD patients [419, 420]